Conserved proximal promoter elements control repulsive guidance molecule c/hemojuvelin (Hfe2) gene transcription in skeletal muscle
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چکیده
منابع مشابه
Temporal and spatial control of murine GATA-3 transcription by promoter-proximal regulatory elements.
GATA-3 is expressed in a temporally dynamic manner and fulfills vital functions during vertebrate fetal development. Homozygous mGATA-3 mutant embryos die at midgestation, thus complicating the analysis of its contribution to the development of specific cell fates in the many tissues where it is expressed during embryogenesis. We show here that the elements controlling GATA-3 regulation can be ...
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anism would thus be a new way to form a tube. As the generation of the lumen and of the tube itself requires the apparition of an apical domain, we decided to investigate how part of the lateral domain becomes apical. Our first results, using transgenes driven by brachyury regulating sequences, show that several proteins classically involved in antero-posterior and planar polarities could be in...
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s: M.G. West, M. Hwang, S. Kadkhodayan, C. Severyn, M.P. Thelen (November 1999).Overexpression in hamster cells of hXRCC1 containing a debilitating mutation in thePARP-binding BRCT domain. American Society for Microbiology (ASM), DNA Repairand Mutagenesis Conference, Hilton Head, SC. UCRL-JC-135806 Abs C. Severyn and P. Rotwein (May 2008) Characterizing RGMc/Hemojuvelin GeneExpr...
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Colorectal cancer (CRC) is one of the most commonly diagnosed cancers and a major cause of cancer death. However, the molecular mechanisms underlying CRC initiation, growth and metastasis are poorly understood. Dragon (RGMb), a member of the repulsive guidance molecule (RGM) family, has been recently identified as a co-receptor for bone morphogenetic protein (BMP) signaling, but the role of Dra...
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ژورنال
عنوان ژورنال: Genomics
سال: 2010
ISSN: 0888-7543
DOI: 10.1016/j.ygeno.2010.09.001